Alpha-ketoglutarate-dependent sulfate ester dioxygenase

BE0003185ProteinPseudomonas putidaatsK

Catalyzes the oxygenolytic cleavage of 2-ethylhexyl sulfate (2-EHS) in the presence of alpha-ketoglutarate to yield 2-ethyl-hexanal and succinate, the decarboxylated form of alpha-ketoglutarate. It is acted on by 1 drug in DrugBank.

Gene name
atsK
UniProtKB entry
Q9WWU5Swiss-Prot
Residues / weight
301 residues · 33,201 Da
Also known as
1.13.11.- · 1.14.11.77 · Alkylsulfatase · Type II alkyl sulfatase

Resolves to

Protein
UniProtQ9WWU5UniProt nameATSK_PSEPU
Structure
PDB1OIHPDB1OIIPDB1OIJ
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Alpha-ketoglutarate-dependent sulfate ester dioxygenase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In