HIV-1 retropepsin

BE0003339ProteinHuman immunodeficiency virus 1pol

HIV-1 retropepsin (Human immunodeficiency virus 1) is a protein target in DrugBank. It is acted on by 3 drugs in DrugBank.

Gene name
pol
UniProtKB entry
Q8Q3H0TrEMBL
Cellular location
Cytoplasmic
Residues / weight
99 residues · 10,793 Da
Also known as
3.4.23.16 · Pepsin A · Pol protein

Resolves to

Protein
UniProtQ8Q3H0UniProt nameQ8Q3H0_HV1
Structure
PDB1WBKPDB1WBMPDB2CEJ
Drugs

What you can answer from here — as of September 08, 2026

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on HIV-1 retropepsin, how selective are they, and which programs against it are still in active trials?

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