C-C chemokine receptor type 2

BE0003387ProteinHumansCCR2

Key functional receptor for CCL2 but can also bind CCL7, and CCL12 (PubMed:23408426, PubMed:38157855, PubMed:8048929, PubMed:8146186). It is acted on by 15 drugs in DrugBank.

Gene name
CCR2
UniProtKB entry
P41597Swiss-Prot
Cellular location
Cell membrane
Residues / weight
374 residues · 41,914 Da
Also known as
C-C CKR-2 · CC-CKR-2 · CCR-2 · CCR2 · CMKBR2

Resolves to

Protein
UniProtP41597UniProt nameCCR2_HUMAN
Gene
HGNCHGNC:1603NCBI Gene729230GeneCardsCCR2
Pharmacology
IUPHAR/GtoPdb59KEGGhsa:729230
Structure
PDB2MLOPDB2MLQPDB5T1A
Drugs

What you can answer from here — as of September 07, 2019

15DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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39GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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47+ReferencesStructured and connected to the statements they support
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Which compounds in development act on C-C chemokine receptor type 2, and which indications are they being tested in?

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