Eotaxin

BE0003389ProteinHumansCCL11

Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells (PubMed:8597956, PubMed:33846499). It is acted on by 1 drug in DrugBank.

Gene name
CCL11
UniProtKB entry
P51671Swiss-Prot
Cellular location
Secreted
Residues / weight
97 residues · 10,732 Da
Also known as
C-C motif chemokine 11 · Eosinophil chemotactic protein · SCYA11 · Small-inducible cytokine A11

Resolves to

Protein
UniProtP51671UniProt nameCCL11_HUMAN
Gene
HGNCHGNC:10610NCBI Gene6356GeneCardsCCL11
Pharmacology
KEGGhsa:6356
Structure
PDB1EOTPDB2EOTPDB2MPM
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Eotaxin, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In