Tumor necrosis factor receptor superfamily member 8

BE0003479ProteinHumansTNFRSF8

Receptor for TNFSF8/CD30L (PubMed:8391931). It is acted on by 7 drugs in DrugBank.

Gene name
TNFRSF8
UniProtKB entry
P28908Swiss-Prot
Cellular location
Cell membrane
Residues / weight
595 residues · 63,746 Da
Also known as
CD30 · CD30L receptor · D1S166E · Ki-1 antigen · Lymphocyte activation antigen CD30

Resolves to

Protein
UniProtP28908UniProt nameTNR8_HUMAN
Gene
HGNCHGNC:11923NCBI Gene943GeneCardsTNFRSF8
Pharmacology
IUPHAR/GtoPdb1877KEGGhsa:943
Structure
PDB1D01
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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57Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor receptor superfamily member 8, how selective are they, and which programs against it are still in active trials?

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