Cytochrome P450 26A1

BE0003480ProteinHumansCYP26A1

A cytochrome P450 monooxygenase involved in the metabolism of retinoates (RAs), the active metabolites of vitamin A, and critical signaling molecules in animals (PubMed:22020119, PubMed:9228017, PubMed:9716180). It is acted on by 5 drugs in DrugBank.

Gene name
CYP26A1
UniProtKB entry
O43174Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
497 residues · 56,198 Da
Also known as
1.14.13.- · CYP26 · CYP26A1 · Cytochrome P450 retinoic acid-inactivating 1 · Cytochrome P450RAI

Resolves to

Protein
UniProtO43174UniProt nameCP26A_HUMAN
Gene
HGNCHGNC:2603NCBI Gene1592GeneCardsCYP26A1
Pharmacology
IUPHAR/GtoPdb1366KEGGhsa:1592
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome P450 26A1, how selective are they, and which programs against it are still in active trials?

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