Carboxypeptidase N subunit 2

BE0003504ProteinHumansCPN2

The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. It is acted on by 5 drugs in DrugBank.

Gene name
CPN2
UniProtKB entry
P22792Swiss-Prot
Cellular location
Secreted
Residues / weight
545 residues · 60,556 Da
Also known as
ACBP · Carboxypeptidase N 83 kDa chain · Carboxypeptidase N large subunit · Carboxypeptidase N polypeptide 2 · Carboxypeptidase N regulatory subunit

Resolves to

Protein
UniProtP22792UniProt nameCPN2_HUMAN
Gene
HGNCHGNC:2313NCBI Gene1370GeneCardsCPN2
Pharmacology
KEGGhsa:1370
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carboxypeptidase N subunit 2, how selective are they, and which programs against it are still in active trials?

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