Serum paraoxonase/lactonase 3

BE0003562ProteinHumansPON3

Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. It is acted on by 4 drugs in DrugBank.

Gene name
PON3
UniProtKB entry
Q15166Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
354 residues · 39,607 Da
Also known as
3.1.1.2 · 3.1.1.81 · 3.1.8.1

Resolves to

Protein
UniProtQ15166UniProt namePON3_HUMAN
Gene
HGNCHGNC:9206NCBI Gene5446GenBank12751374GeneCardsPON3
Pharmacology
KEGGhsa:5446
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serum paraoxonase/lactonase 3, how selective are they, and which programs against it are still in active trials?

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