Voltage-dependent calcium channel subunit alpha-2/delta-3

BE0003563ProteinHumansCACNA2D3

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. It is acted on by 2 drugs in DrugBank.

Gene name
CACNA2D3
UniProtKB entry
Q8IZS8Swiss-Prot
Cellular location
Membrane
Residues / weight
1,091 residues · 123,010 Da
Also known as
Voltage-gated calcium channel subunit alpha-2/delta-3

Resolves to

Protein
UniProtQ8IZS8UniProt nameCA2D3_HUMAN
Gene
HGNCHGNC:15460NCBI Gene55799GenBank7105926GeneCardsCACNA2D3
Pharmacology
KEGGhsa:55799
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent calcium channel subunit alpha-2/delta-3, how selective are they, and which programs against it are still in active trials?

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