Nischarin

BE0003580ProteinHumansNISCH

Acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling. It is acted on by 8 drugs in DrugBank.

Gene name
NISCH
UniProtKB entry
Q9Y2I1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,504 residues · 166,627 Da
Also known as
hIRAS · I-1 · I-1 receptor candidate protein · I1R · I1R candidate protein

Resolves to

Protein
UniProtQ9Y2I1UniProt nameNISCH_HUMAN
Gene
HGNCHGNC:18006NCBI Gene11188GenBank3462807GeneCardsNISCH
Pharmacology
KEGGhsa:11188
Structure
PDB3P0CPDB8ESF
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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39+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nischarin, how selective are they, and which programs against it are still in active trials?

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