Rilmenidine

DB11738ApprovedWithdrawnSmall molecule

Rilmenidine is an I1-imidazoline receptor agonist used to treat hypertension. Rilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.

Mechanism: Pharmacologically active on Nischarin
Curator reviewed
Formula / weight: C₁₀H₁₆N₂O · 180.251 g/mol (avg)
Also known as: HYPERIUM

Resolves to

Compound

UNIIP67IM25ID8CAS54187-04-1ChEMBLCHEMBL289480ChEBI8862PubChem68712KEGGC11120

Clinical / RWD

RxNorm55679ATCC02AC06

Structure

InChIKeyCQXADFVORZEARL-UHFFFAOYSA-NSMILESC1CC1C(NC1=NCCO1)C1CC1

Targets

Q9Y2I1NISCHP18825ADRA2CP08913ADRA2A

What you can answer from here — as of August 30, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

760Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

3ContraindicationsEach with its own population and attribute set

7Marketed productsAcross 4 countries and 7 labellers

1ATC codeIncluding every combination product, plus 15 drug categories

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Rilmenidine, and which of those have an active Phase 3 trial?

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