Nuclear receptor coactivator 2

BE0003740ProteinHumansNCOA2

Transcriptional coactivator for steroid receptors and nuclear receptors (PubMed:23508108, PubMed:8670870, PubMed:9430642, PubMed:22504882, PubMed:26553876). It is acted on by 29 drugs in DrugBank.

Gene name
NCOA2
UniProtKB entry
Q15596Swiss-Prot
Cellular location
Nucleus
Residues / weight
1,464 residues · 159,156 Da
Also known as
BHLHE75 · Class E basic helix-loop-helix protein 75 · hTIF2 · NCoA-2 · SRC2

Resolves to

Protein
UniProtQ15596UniProt nameNCOA2_HUMAN
Gene
HGNCHGNC:7669NCBI Gene10499GenBank1877215GeneCardsNCOA2
Pharmacology
KEGGhsa:10499
Structure
PDB1GWQPDB1GWRPDB1M2Z
Drugs

What you can answer from here — as of September 07, 2019

29DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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8Pfam domainsDomain architecture mapped to Pfam families and clans
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53+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nuclear receptor coactivator 2, how selective are they, and which programs against it are still in active trials?

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