Chymotrypsin-like elastase family member 1

BE0003758ProteinHumansCELA1

Serine proteases that hydrolyze many proteins in addition to elastin. It is acted on by 21 drugs in DrugBank.

Gene name
CELA1
UniProtKB entry
Q9UNI1Swiss-Prot
Cellular location
Secreted
Residues / weight
258 residues · 27,798 Da
Also known as
3.4.21.36 · ELA1 · Elastase-1 · Pancreatic elastase 1

Resolves to

Protein
UniProtQ9UNI1UniProt nameCELA1_HUMAN
Gene
HGNCHGNC:3308NCBI Gene1990GenBank4731318GeneCardsCELA1
Pharmacology
IUPHAR/GtoPdb2338KEGGhsa:1990
Drugs

What you can answer from here — as of September 07, 2019

21DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Chymotrypsin-like elastase family member 1, how selective are they, and which programs against it are still in active trials?

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