Sivelestat

DB12863InvestigationalSmall molecule

Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.

Chemical structure of Sivelestat
Mechanism
Curator reviewed
Formula / weight
C20H22N2O7S · 434.46 g/mol (avg)

Resolves to

Compound
UNIIDWI62G0P59CAS127373-66-4ChEMBLCHEMBL76688ChEBI135704PubChem107706
Structure
InChIKeyBTGNGJJLZOIYID-UHFFFAOYSA-NSMILESCC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=C1C(=O)NCC(O)=O
Targets
P08246ELANEQ9UNI1CELA1

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
18Clinical trialsPhase, status and sponsor resolved per trial
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7+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sivelestat, and which of those have an active Phase 3 trial?

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