Death-associated protein kinase 3

BE0003788ProteinHumansDAPK3

Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. It is acted on by 4 drugs in DrugBank.

Gene name
DAPK3
UniProtKB entry
O43293Swiss-Prot
Cellular location
Nucleus
Residues / weight
454 residues · 52,535 Da
Also known as
2.7.11.1 · DAP kinase 3 · DAP-like kinase · Dlk · MYPT1 kinase

Resolves to

Protein
UniProtO43293UniProt nameDAPK3_HUMAN
Gene
HGNCHGNC:2676NCBI Gene1613GenBank2911156GeneCardsDAPK3
Pharmacology
IUPHAR/GtoPdb2004KEGGhsa:1613
Structure
PDB1YRPPDB2J90PDB3BHY
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
27GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
31+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Death-associated protein kinase 3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In