2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one

Star0

DB04716ExperimentalSmall molecule

2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one: Overview.

Mechanism: Pharmacologically active on Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, and Non-receptor tyrosine-protein kinase TYK2
Curator reviewed
Formula / weight: C₁₈H₁₆FN₃O · 309.3375 g/mol (avg)
Also known as: CMP 6 · Pyridone 6

Resolves to

Compound

UNIILDX3F0CCSTCAS457081-03-7ChEMBLCHEMBL21156ChEBI87103PubChem5494425

Structure

InChIKeyVNDWQCSOSCCWIP-UHFFFAOYSA-NSMILESCC(C)(C)C1=NC2=C3C=CNC(=O)C3=C3C=C(F)C=CC3=C2N1

Targets

O60674JAK2P52333JAK3P29597TYK2O43293DAPK3P23458JAK1

What you can answer from here — as of September 23, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

20+ReferencesStructured and connected to the statements they support

Which drugs share a target with 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account