Peptide deformylase

BE0003873ProteinLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 1 drug in DrugBank.

Gene name
def
UniProtKB entry
Q93LE9Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
178 residues · 20,379 Da
Also known as
3.5.1.88 · pdf · Polypeptide deformylase

Resolves to

Protein
UniProtQ93LE9UniProt nameDEF_LEPIN
Gene
NCBI Gene1151781GenBank14626937
Pharmacology
KEGGlil:LA_2438
Structure
PDB1SV2PDB1SZZPDB1VEV
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase, and which indications are they being tested in?

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