Peptide deformylase 1

BE0003874ProteinBacillus cereus (strain ATCC 14579 / DSM 31)def1

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 1 drug in DrugBank.

Gene name
def1
UniProtKB entry
Q819U0Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
156 residues · 17,480 Da
Also known as
3.5.1.88 · PDF 1 · Polypeptide deformylase 1

Resolves to

Protein
UniProtQ819U0UniProt nameDEF1_BACCR
Gene
NCBI Gene1206210GenBank29893819
Pharmacology
KEGGbce:BC3865
Structure
PDB1WS0PDB1WS1
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase 1, and which indications are they being tested in?

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