Peptide deformylase

BE0003876ProteinEnterococcus faecalis (strain ATCC 700802 / V583)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 1 drug in DrugBank.

Gene name
def
UniProtKB entry
Q82ZJ0Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
187 residues · 20,912 Da
Also known as
3.5.1.88 · PDF · Polypeptide deformylase

Resolves to

Protein
UniProtQ82ZJ0UniProt nameDEF_ENTFA
Gene
NCBI Gene1201912GenBank29342120
Pharmacology
KEGGefa:EF3066
Structure
PDB2OS0PDB2OS1
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase, and which indications are they being tested in?

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