Cytochrome c oxidase subunit 2
Details
- Name
- Cytochrome c oxidase subunit 2
- Kind
- protein
- Synonyms
- 1.9.3.1
- ctaC
- Cytochrome c ba(3) subunit II
- Cytochrome c oxidase polypeptide II
- Cytochrome cba3 subunit 2
- Gene Name
- cbaB
- UniProtKB Entry
- Q5SJ80Swiss-Prot
- Organism
- Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
- NCBI Taxonomy ID
- 300852
- Amino acid sequence
>lcl|BSEQ0019491|Cytochrome c oxidase subunit 2 MVDEHKAHKAILAYEKGWLAFSLAMLFVFIALIAYTLATHTAGVIPAGKLERVDPTTVRQ EGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEG TNINVEVLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE
- Number of residues
- 168
- Molecular Weight
- 18563.305
- Theoretical pI
- 6.51
- GO Classification
- Functionscopper ion binding / cytochrome-c oxidase activityProcesseselectron transport chainComponentsintegral component of membrane / plasma membrane / respiratory chain
- General Function
- Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
- Specific Function
- copper ion binding
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- 4-38
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0019492|Cytochrome c oxidase subunit 2 (cbaB) ATGGTGGACGAGCACAAGGCCCACAAGGCGATCCTGGCCTACGAGAAGGGGTGGCTCGCC TTCTCCTTGGCGATGCTCTTCGTCTTCATCGCCCTCATCGCCTACACCCTGGCCACCCAC ACCGCCGGGGTCATTCCCGCCGGAAAGCTTGAGCGCGTGGACCCCACCACGGTAAGGCAG GAAGGCCCCTGGGCCGACCCGGCCCAAGCGGTGGTGCAGACCGGCCCCAACCAGTACACG GTCTACGTCCTGGCCTTCGCCTTCGGCTACCAGCCGAACCCCATTGAGGTGCCCCAAGGG GCGGAGATCGTCTTCAAGATCACGAGCCCGGACGTGATCCACGGCTTTCACGTGGAGGGC ACCAACATCAACGTGGAGGTGCTCCCGGGCGAGGTCTCCACCGTGCGCTACACCTTCAAA AGGCCCGGGGAGTACCGCATCATCTGCAACCAGTACTGCGGCCTAGGCCACCAGAACATG TTCGGCACGATCGTGGTGAAGGAGTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q5SJ80 UniProtKB Entry Name COX2_THET8 GenBank Protein ID 5053134 GenBank Gene ID L09121 PDB ID(s) 1EHK, 2QPD, 2QPE, 3BVD, 3EH3, 3EH4, 3EH5, 3QJQ, 3QJR, 3QJS, 3QJT, 3QJU, 3QJV, 3S33, 3S38, 3S39, 3S3A, 3S3B, 3S3C, 3S3D, 3S8F, 3S8G, 4FA7, 4FAA, 4G70, 4G71, 4G72, 4G7Q, 4G7R, 4G7S, 4GP4, 4GP5, 4GP8, 4N4Y KEGG ID ttj:TTHA1134 NCBI Gene ID 3169672 - General References
- Keightley JA, Zimmermann BH, Mather MW, Springer P, Pastuszyn A, Lawrence DM, Fee JA: Molecular genetic and protein chemical characterization of the cytochrome ba3 from Thermus thermophilus HB8. J Biol Chem. 1995 Sep 1;270(35):20345-58. [Article]
- Soulimane T, Buse G, Bourenkov GP, Bartunik HD, Huber R, Than ME: Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus. EMBO J. 2000 Apr 17;19(8):1766-76. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details B-nonylglucoside experimental unknown target Details