Proteasome subunit beta type-6

BE0003919ProteinHumansPSMB6

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMB6
UniProtKB entry
P28072Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
239 residues · 25,357 Da
Also known as
3.4.25.1 · beta-1 · LMPY · Macropain delta chain · Multicatalytic endopeptidase complex delta chain

Resolves to

Protein
UniProtP28072UniProt namePSB6_HUMAN
Gene
HGNCHGNC:9543NCBI Gene5694GenBank558528GeneCardsPSMB6
Pharmacology
KEGGhsa:5694
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
17GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Proteasome subunit beta type-6, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In