Guanine nucleotide-binding protein G(t) subunit alpha-1

BE0003945ProteinHumansGNAT1

Alpha subunit of the heterotrimeric guanine nucleotide-binding protein (G protein) that transduces signals from the G protein-coupled photoreceptor rhodopsin (RHO). It is acted on by 3 drugs in DrugBank.

Gene name
GNAT1
UniProtKB entry
P11488Swiss-Prot
Cellular location
Photoreceptor outer segment membrane
Residues / weight
350 residues · 40,040 Da
Also known as
3.6.5.- · GNATR · Rod transducin · Transducin alpha-1 chain

Resolves to

Protein
UniProtP11488UniProt nameGNAT1_HUMAN
Gene
HGNCHGNC:4393NCBI Gene2779GenBank31865GeneCardsGNAT1
Pharmacology
KEGGhsa:2779
Structure
PDB3RBQ
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Guanine nucleotide-binding protein G(t) subunit alpha-1, and which indications are they being tested in?

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