Histone deacetylase-like amidohydrolase

BE0003985ProteinAlcaligenes sp. (strain DSM 11172)hdaH

Exhibits significant levels of protein deacetylase activity comparable to those of eukaryotic HDACs in assays both with fluorogenic peptidic substrates and acetate-radiolabeled histones. It is acted on by 2 drugs in DrugBank.

Gene name
hdaH
UniProtKB entry
Q70I53Swiss-Prot
Residues / weight
369 residues · 39,423 Da
Also known as
3.5.1.- · HDAC-like amidohydrolase · hdaH1

Resolves to

Protein
UniProtQ70I53UniProt nameHDAH_ALCSD
Gene
GenBank37496190
Structure
PDB1ZZ0PDB1ZZ1PDB1ZZ3
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Histone deacetylase-like amidohydrolase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In