Very low-density lipoprotein receptor

BE0004020ProteinHumansVLDLR

Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. It is acted on by 6 drugs in DrugBank.

Gene name
VLDLR
UniProtKB entry
P98155Swiss-Prot
Cellular location
Cell membrane
Residues / weight
873 residues · 96,097 Da
Also known as
VLDL receptor · VLDL-R

Resolves to

Protein
UniProtP98155UniProt nameVLDLR_HUMAN
Gene
HGNCHGNC:12698NCBI Gene7436GenBank409426GeneCardsVLDLR
Pharmacology
KEGGhsa:7436
Structure
PDB1V9UPDB3DPRPDB6BYV
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
16GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
18+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Very low-density lipoprotein receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In