D-alanine--D-alanine ligase

BE0004095ProteinStaphylococcus aureus (strain COL)ddl

Cell wall formation. It is acted on by 1 drug in DrugBank.

Gene name
ddl
UniProtKB entry
Q5HEB7Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
356 residues · 40,230 Da
Also known as
6.3.2.4 · D-Ala-D-Ala ligase · D-alanylalanine synthetase

Resolves to

Protein
UniProtQ5HEB7UniProt nameDDL_STAAC
Gene
NCBI Gene23197880GenBank57285295
Pharmacology
KEGGsac:SACOL2074
Structure
PDB2I80PDB2I87PDB2I8C
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on D-alanine--D-alanine ligase, and which indications are they being tested in?

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