Calcium/calmodulin-dependent protein kinase type II subunit delta

BE0004108ProteinHumansCAMK2D

Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the... It is acted on by 4 drugs in DrugBank.

Gene name
CAMK2D
UniProtKB entry
Q13557Swiss-Prot
Cellular location
Cell membrane, sarcolemma
Residues / weight
499 residues · 56,369 Da
Also known as
2.7.11.17 · CaM kinase II subunit delta · CaMK-II subunit delta · CAMKD

Resolves to

Protein
UniProtQ13557UniProt nameKCC2D_HUMAN
Gene
HGNCHGNC:1462NCBI Gene817GeneCardsCAMK2D
Pharmacology
IUPHAR/GtoPdb1558KEGGhsa:817
Structure
PDB2VN9PDB2W2CPDB2WEL
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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37GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium/calmodulin-dependent protein kinase type II subunit delta, how selective are they, and which programs against it are still in active trials?

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