Rimacalib

DB12571InvestigationalSmall molecule

Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).

Chemical structure of Rimacalib
Formula / weight
C22H23FN4O2 · 394.45 g/mol (avg)
Code names
SMP-114

Resolves to

Compound
UNIIBZ76J3N815CAS215174-50-8ChEMBLCHEMBL2107772PubChem9800765
Structure
InChIKeyMYTIJGWONQOOLC-HNNXBMFYSA-NSMILES[H][C@@](C)(C1=NOC(NC(=N)N2CCOCC2)=C1)C1=CC=C(C(F)=C1)C1=CC=CC=C1
Targets
Q13555CAMK2GQ13557CAMK2DQ13554CAMK2BQ9UQM7CAMK2A

What you can answer from here — as of January 29, 2025

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Rimacalib, and which of those have an active Phase 3 trial?

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