Dihydrofolate reductase

BE0004248ProteinBacillus anthracisdfrA

Key enzyme in folate metabolism. It is acted on by 1 drug in DrugBank.

Gene name
dfrA
UniProtKB entry
Q81R22TrEMBL
Residues / weight
162 residues · 19,125 Da
Also known as
1.5.1.3 · dfrD

Resolves to

Protein
UniProtQ81R22UniProt nameQ81R22_BACAN
Gene
GenBank30253517
Pharmacology
KEGGbanh:HYU01_11160
Structure
PDB2KGKPDB2QK8PDB3DAT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dihydrofolate reductase, and which indications are they being tested in?

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