Myosin-7

BE0004294ProteinHumansMYH7

Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. It is acted on by 4 drugs in DrugBank.

Gene name
MYH7
UniProtKB entry
P12883Swiss-Prot
Cellular location
Cytoplasm, myofibril
Residues / weight
1,935 residues · 223,096 Da
Also known as
MyHC-beta · MyHC-slow · MYHCB · Myosin heavy chain 7 · Myosin heavy chain slow isoform

Resolves to

Protein
UniProtP12883UniProt nameMYH7_HUMAN
Gene
HGNCHGNC:7577NCBI Gene4625GenBank179510GeneCardsMYH7
Pharmacology
KEGGhsa:4625
Structure
PDB2FXMPDB2FXOPDB3DTP
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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94+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Myosin-7, how selective are they, and which programs against it are still in active trials?

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