Cytochrome c-552

BE0004303ProteinThioalkalivibrio nitratireducensnir

Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process (PubMed:16500161, PubMed:22281743). It is acted on by 1 drug in DrugBank.

Gene name
nir
UniProtKB entry
L0DSL2Swiss-Prot
Cellular location
Periplasm
Residues / weight
553 residues · 62,344 Da
Also known as
1.7.2.2 · Cytochrome c nitrite reductase · TvNiR

Resolves to

Protein
UniProtL0DSL2UniProt nameNIR_THIND
Gene
GenBank73661133
Pharmacology
KEGGtni:TVNIR_0259
Structure
PDB2OT4PDB2ZO5PDB3D1I
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome c-552, and which indications are they being tested in?

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