Serpin B3

BE0004463ProteinHumansSERPINB3

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It is acted on by 2 drugs in DrugBank.

Gene name
SERPINB3
UniProtKB entry
P29508Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
390 residues · 44,564 Da
Also known as
Protein T4-A · SCCA · SCCA-1 · SCCA1 · Squamous cell carcinoma antigen 1

Resolves to

Protein
UniProtP29508UniProt nameSPB3_HUMAN
Gene
HGNCHGNC:10569NCBI Gene6317GeneCardsSERPINB3
Pharmacology
KEGGhsa:6317
Structure
PDB2ZV6PDB4ZK0PDB4ZK3
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serpin B3, how selective are they, and which programs against it are still in active trials?

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