Galectin-1

BE0004493ProteinHumansLGALS1

Lectin that binds beta-galactoside and a wide array of complex carbohydrates. It is acted on by 6 drugs in DrugBank.

Gene name
LGALS1
UniProtKB entry
P09382Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
135 residues · 14,716 Da
Also known as
14 kDa laminin-binding protein · 14 kDa lectin · Beta-galactoside-binding lectin L-14-I · Gal-1 · Galaptin

Resolves to

Protein
UniProtP09382UniProt nameLEG1_HUMAN
Gene
HGNCHGNC:6561NCBI Gene3956GeneCardsLGALS1
Pharmacology
KEGGhsa:3956
Structure
PDB1GZWPDB1W6MPDB1W6N
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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46+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Galectin-1, how selective are they, and which programs against it are still in active trials?

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