Transforming growth factor beta-3 proprotein

BE0004506ProteinHumansTGFB3

Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. It is acted on by 6 drugs in DrugBank.

Gene name
TGFB3
UniProtKB entry
P10600Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
412 residues · 47,328 Da

Resolves to

Protein
UniProtP10600UniProt nameTGFB3_HUMAN
Gene
HGNCHGNC:11769NCBI Gene7043GeneCardsTGFB3
Pharmacology
KEGGhsa:7043
Structure
PDB1KTZPDB1TGJPDB1TGK
Drugs

What you can answer from here — as of September 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
28GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
26+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Transforming growth factor beta-3 proprotein, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In