Fresolimumab

DB12396InvestigationalProtein Based Therapies

Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.

Mechanism: Pharmacologically active on Transforming growth factor beta-1 proprotein, Transforming growth factor beta-2 proprotein, and Transforming growth factor beta-3 proprotein
Curator reviewed
Also known as: GC1008

Resolves to

Compound

UNII375142VBIACAS948564-73-6

Targets

P01137TGFB1P61812TGFB2P10600TGFB3

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

381Drug interactionsStructured to mechanism, not free text

11Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Fresolimumab, and which of those have an active Phase 3 trial?

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