Serine/threonine-protein kinase TAO2

BE0004632ProteinHumansTAOK2

Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. It is acted on by 2 drugs in DrugBank.

Gene name
TAOK2
UniProtKB entry
Q9UL54Swiss-Prot
Cellular location
Cytoplasmic vesicle membrane
Residues / weight
1,235 residues · 138,250 Da
Also known as
2.7.11.1 · hKFC-C · KIAA0881 · Kinase from chicken homolog C · MAP3K17

Resolves to

Protein
UniProtQ9UL54UniProt nameTAOK2_HUMAN
Gene
HGNCHGNC:16835NCBI Gene9344GeneCardsTAOK2
Pharmacology
IUPHAR/GtoPdb2234KEGGhsa:9344
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase TAO2, how selective are they, and which programs against it are still in active trials?

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