Small ribosomal subunit protein uS7

BE0004653ProteinEscherichia coli (strain K12)rpsG

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit (PubMed:2461734). It is acted on by 4 drugs in DrugBank.

Gene name
rpsG
UniProtKB entry
P02359Swiss-Prot
Residues / weight
179 residues · 20,019 Da
Also known as
30S ribosomal protein S7

Resolves to

Protein
UniProtP02359UniProt nameRS7_ECOLI
Gene
NCBI Gene947846
Pharmacology
KEGGecj:JW3303
Structure
PDB1EG0PDB1M5GPDB1ML5
Drugs

What you can answer from here — as of May 03, 2025

4DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Small ribosomal subunit protein uS7, how selective are they, and which programs against it are still in active trials?

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