1,3-beta-glucan synthase component FKS1

BE0004669ProteinAspergillus niger (strain CBS 513.88 / FGSC A1513)fksA

Catalytic subunit of the 1,3-beta-glucan synthase. It is acted on by 4 drugs in DrugBank.

Gene name
fksA
UniProtKB entry
A2QLK4Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
1,897 residues · 216,973 Da
Also known as
1,3-beta-D-glucan-UDP glucosyltransferase · 2.4.1.34 · fks1

Resolves to

Protein
UniProtA2QLK4UniProt nameFKS1_ASPNC
Gene
NCBI Gene4981154
Pharmacology
KEGGang:ANI_1_188054
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 1,3-beta-glucan synthase component FKS1, how selective are they, and which programs against it are still in active trials?

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