Cobalamin binding intrinsic factor

BE0004690ProteinHumansCBLIF

Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. It is acted on by 2 drugs in DrugBank.

Gene name
CBLIF
UniProtKB entry
P27352Swiss-Prot
Cellular location
Secreted
Residues / weight
417 residues · 45,416 Da
Also known as
Gastric intrinsic factor · GIF · IF · IFMH · INF

Resolves to

Protein
UniProtP27352UniProt nameIF_HUMAN
Gene
HGNCHGNC:4268NCBI Gene2694GeneCardsCBLIF
Pharmacology
KEGGhsa:2694
Structure
PDB2PMVPDB3KQ4
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cobalamin binding intrinsic factor, how selective are they, and which programs against it are still in active trials?

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