Genome polyprotein

Details

Name
Genome polyprotein
Kind
protein
Synonyms
Not Available
Gene Name
NS3/4A
UniProtKB Entry
B0B3C9TrEMBL
Organism
Hepatitis C Virus
NCBI Taxonomy ID
11103
Amino acid sequence
>lcl|BSEQ0021396|Genome polyprotein
APITAYAQQTRGLLGTIVTGLTGRDKNVVTGEVQVLSTATQTFLGTTVGGVMWTVYHGAG
SRTLAGAKHPALQMYTNVDQDLVGWPAPSGAKSLEPCACGSADLYLITRDADVIPARRRG
DSTASLLSPRPLACLKGSSGGPVMCPSGHVAGIFRAAVCTRGVAKALQFIPVETLSTQAR
SPSFSDNSTPPAVPQSYQVGYLHAPTGSGKSTKVPAAYVAQGYNVLVLNPSVAATLGFGS
FMSRAYGVDPNIRTGNRTVTTGAKLTYSTYGKFLADGGCSGGAYDVIICDECHAQDATSI
LGIGTVLDQAETAGVRLTVLATATPPGSITVPHSNIEEVALGSEGEIPFYGKAIPIALLK
GGRHLIFCHSKKKCEEIASKLRGMGLNAVAYYRGLDVSVIPTTGDVVVCATDALMTGYTG
DFDSVIDCNVAVEQYVDFSLDPTFSIETRTAPQDAVSRSQRRGRTGRGRLGTYRYVAPGE
RPSGMFDSVVLCECYDAGCSWYDLQPAETTVRLRAYLSTPGLPVCQDHLDFWESVFTGLT
HIDAHFLSQTKQQGLNFSYLTAYQATVCARAQAPPPSWDETWKCLVRLKPTLHGPTPLLY
RLGPIQNETCLTHPVTKYIMACMSADLEVTTSTWVLLGGVLAALAAYCLSVGSVVIVGHI
ELGGKPALVPDREVLYQQYDEMEEC
Number of residues
685
Molecular Weight
72789.28
Theoretical pI
Not Available
GO Classification
Functions
ATP binding / ATP-dependent helicase activity / RNA-directed RNA polymerase activity / serine-type peptidase activity
Processes
transformation of host cell by virus / viral genome replication
Components
virion
General Function
Serine-type peptidase activity
Specific Function
Not Available
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDB0B3C9
UniProtKB Entry NameB0B3C9_9HEPC
General References
Not Available

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Telaprevirapproved, withdrawnyestargetinhibitorDetails
Boceprevirapproved, withdrawnyestargetinhibitorDetails
Paritaprevirapproved, investigationalyestargetinhibitorDetails
GrazoprevirapprovedyestargetantagonistDetails
Voxilaprevirapproved, investigationalyestargetinhibitorDetails
SimeprevirapprovedyestargetinhibitorDetails
Glecaprevirapproved, investigationalyestargetinhibitorDetails