Sodium-dependent organic anion transporter

BE0004710ProteinHumansSLC10A6

Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis (PubMed:17491011, PubMed:23667501, PubMed:24717977, PubMed:28951227). It is acted on by 3 drugs in DrugBank.

Gene name
SLC10A6
UniProtKB entry
Q3KNW5Swiss-Prot
Cellular location
Membrane
Residues / weight
377 residues · 41,258 Da
Also known as
SLC10A6 · SOAT · Solute carrier family 10 member 6

Resolves to

Protein
UniProtQ3KNW5UniProt nameSOAT_HUMAN
Gene
HGNCHGNC:30603NCBI Gene345274GeneCardsSLC10A6
Pharmacology
KEGGhsa:345274
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent organic anion transporter, how selective are they, and which programs against it are still in active trials?

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