Discoidin domain-containing receptor 2

BE0004741ProteinHumansDDR2

Tyrosine kinase involved in the regulation of tissues remodeling (PubMed:30449416). It is acted on by 5 drugs in DrugBank.

Gene name
DDR2
UniProtKB entry
Q16832Swiss-Prot
Cellular location
Cell membrane
Residues / weight
855 residues · 96,735 Da
Also known as
2.7.10.1 · CD167 antigen-like family member B · Discoidin domain receptor 2 · Discoidin domain-containing receptor tyrosine kinase 2 · Neurotrophic tyrosine kinase, receptor-related 3

Resolves to

Protein
UniProtQ16832UniProt nameDDR2_HUMAN
Gene
HGNCHGNC:2731NCBI Gene4921GeneCardsDDR2
Pharmacology
IUPHAR/GtoPdb1844KEGGhsa:4921
Structure
PDB2WUHPDB2Z4FPDB6FER
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
22GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
30+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Discoidin domain-containing receptor 2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In