RNA-directed RNA polymerase lambda-3

BE0004792ProteinT3DL1

RNA-directed RNA polymerase that is involved in transcription and genome replication. It is acted on by 1 drug in DrugBank.

Gene name
L1
UniProtKB entry
P0CK31Swiss-Prot
Cellular location
Virion
Residues / weight
1,267 residues · 142,269 Da
Also known as
2.7.7.48 · Lambda3 · Lambda3(Pol)

Resolves to

Protein
UniProtP0CK31UniProt nameRDRP_REOVD
Gene
GenBank499864
Structure
PDB1MUKPDB1MWHPDB1N1H
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on RNA-directed RNA polymerase lambda-3, and which indications are they being tested in?

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