Solute carrier family 52, riboflavin transporter, member 2

BE0004841ProteinHumansSLC52A2

Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:20463145, PubMed:22864630, PubMed:23243084, PubMed:24253200,... It is acted on by 3 drugs in DrugBank.

Gene name
SLC52A2
UniProtKB entry
Q9HAB3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
445 residues · 45,777 Da
Also known as
GPR172A · hRFT3 · PAR1 · PERV-A receptor 1 · Porcine endogenous retrovirus A receptor 1

Resolves to

Protein
UniProtQ9HAB3UniProt nameS52A2_HUMAN
Gene
HGNCHGNC:30224NCBI Gene79581GeneCardsSLC52A2
Pharmacology
KEGGhsa:79581
Structure
PDB8XSM
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 52, riboflavin transporter, member 2, how selective are they, and which programs against it are still in active trials?

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