POU domain, class 2, transcription factor 2

BE0004865ProteinHumansPOU2F2

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). It is acted on by 3 drugs in DrugBank.

Gene name
POU2F2
UniProtKB entry
P09086Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
479 residues · 51,209 Da
Also known as
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 · Oct-2 · OCT2 · Octamer-binding protein 2 · Octamer-binding transcription factor 2

Resolves to

Protein
UniProtP09086UniProt namePO2F2_HUMAN
Gene
HGNCHGNC:9213NCBI Gene5452GeneCardsPOU2F2
Pharmacology
KEGGhsa:5452
Structure
PDB1HDPPDB9DZM
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on POU domain, class 2, transcription factor 2, how selective are they, and which programs against it are still in active trials?

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