Solute carrier family 2, facilitated glucose transporter member 8

BE0005219ProteinHumansSLC2A8

Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
SLC2A8
UniProtKB entry
Q9NY64Swiss-Prot
Cellular location
Cell membrane
Residues / weight
477 residues · 50,819 Da
Also known as
Glucose transporter type 8 · Glucose transporter type X1 · GLUT-8 · GLUT8 · GLUTX1

Resolves to

Protein
UniProtQ9NY64UniProt nameSL2A8_HUMAN
Gene
HGNCHGNC:13812NCBI Gene29988GeneCardsSLC2A8
Pharmacology
KEGGhsa:29988
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 2, facilitated glucose transporter member 8, how selective are they, and which programs against it are still in active trials?

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