NADPH oxidase 1

BE0005803ProteinHumansNOX1

NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. It is acted on by 3 drugs in DrugBank.

Gene name
NOX1
UniProtKB entry
Q9Y5S8Swiss-Prot
Cellular location
Cell projection, invadopodium membrane
Residues / weight
564 residues · 64,870 Da
Also known as
1.6.3.- · Mitogenic oxidase 1 · MOX-1 · MOX1 · NADH/NADPH mitogenic oxidase subunit P65-MOX

Resolves to

Protein
UniProtQ9Y5S8UniProt nameNOX1_HUMAN
Gene
HGNCHGNC:7889NCBI Gene27035GeneCardsNOX1
Pharmacology
IUPHAR/GtoPdb3001KEGGhsa:27035
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADPH oxidase 1, how selective are they, and which programs against it are still in active trials?

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