Oxygen is an essential element for human survival used in clinical conditions in which there is a lack of oxygen, such as, but not limited to, anoxia, hypoxia or dyspnea. Oxygen is an element displayed by the symbol O, and atomic number 8.
- Mechanism
- Curator reviewed · 1 reference
Oxygen therapy increases the arterial pressure of oxygen and is effective in improving gas exchange and oxygen delivery to tissues, provided that there are functional alveolar units. Oxygen plays a critical role as an electron acceptor during oxidative phosphorylation in the electron transport chain through activation of cytochrome c oxidase (terminal enzyme of the electron transport chain). This process achieves successful aerobic respiration in organisms to generate ATP molecules as an energy source in many tissues. Oxygen supplementation acts to restore normal cellular activity at the mitochondrial level and reduce metabolic acidosis. There is also evidence that oxygen may interact with O2-sensitive voltage-gated potassium channels in glomus cells and cause hyperpolarization of mitochondrial membrane.
- Primary indication
- Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption...Curator reviewed · 11 structured indications
- Formula / weight
- O2 · 31.9988 g/mol (avg)
- First approval
- Canada, 1998 · United States, 1919
- Also known as
- Dioxygen · Molecular oxygen · Oxygen USP · Pure oxygen
- Code names
- E-948 · INS-948 · INS NO.948
- Brand names
Resolves to
MYMOFIZGZYHOMD-UHFFFAOYSA-NSMILESO=OWhat you can answer from here — as of May 03, 2025
Which drugs share a target with Oxygen, and which of those have an active Phase 3 trial?
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