Alpha-enolase

BE0005807ProteinHumansENO1

Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (PubMed:1369209, PubMed:29775581). It is acted on by 7 drugs in DrugBank.

Gene name
ENO1
UniProtKB entry
P06733Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
434 residues · 47,169 Da
Also known as
2-phospho-D-glycerate hydro-lyase · 4.2.1.11 · C-myc promoter-binding protein · ENO1L1 · Enolase 1

Resolves to

Protein
UniProtP06733UniProt nameENOA_HUMAN
Gene
HGNCHGNC:3350NCBI Gene2023GeneCardsENO1
Pharmacology
KEGGhsa:2023
Structure
PDB2PSNPDB3B97PDB5JLZ
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
16GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
44+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Alpha-enolase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In