Thyrotropin-releasing hormone receptor

BE0008659ProteinHumansTRHR

Receptor for thyrotropin-releasing hormone (TRH). It is acted on by 6 drugs in DrugBank.

Gene name
TRHR
UniProtKB entry
P34981Swiss-Prot
Cellular location
Cell membrane
Residues / weight
398 residues · 45,084 Da
Also known as
Thyroliberin receptor · TRH-R

Resolves to

Protein
UniProtP34981UniProt nameTRFR_HUMAN
Gene
HGNCHGNC:12299NCBI Gene7201GeneCardsTRHR
Pharmacology
IUPHAR/GtoPdb363KEGGhsa:7201
Structure
PDB7WKDPDB7X1TPDB7X1U
Drugs

What you can answer from here — as of September 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thyrotropin-releasing hormone receptor, how selective are they, and which programs against it are still in active trials?

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