Alpha-hemoglobin-stabilizing protein

BE0008990ProteinHumansAHSP

Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. It is acted on by 6 drugs in DrugBank.

Gene name
AHSP
UniProtKB entry
Q9NZD4Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
102 residues · 11,840 Da
Also known as
EDRF · ERAF · Erythroid differentiation-related factor · Erythroid-associated factor

Resolves to

Protein
UniProtQ9NZD4UniProt nameAHSP_HUMAN
Gene
HGNCHGNC:18075NCBI Gene51327GeneCardsAHSP
Pharmacology
KEGGhsa:51327
Structure
PDB1W09PDB1W0APDB1W0B
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alpha-hemoglobin-stabilizing protein, how selective are they, and which programs against it are still in active trials?

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